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Tramadol narcotic to treat moderate to severe pain.


Generic Name : tramadol (TRAM a dol)
Brand Names :
ConZip, Rybix ODT, Ryzolt, Ultram


* What is tramadol?

- Tramadol is a narcotic-like pain reliever.
- Tramadol is used to treat moderate to severe pain.
- The extended-release form of tramadol is for around-the-clock treatment of pain.

- This form of tramadol is not for use on an as-needed basis for pain.


* notice those Important information :
- You should not take tramadol if you have used alcohol, sedatives, tranquilizers, or narcotic medications within the past few hours.

- Tramadol can slow or stop your breathing, especially when you start using this medicine or whenever your dose is changed. 


- Never take tramadol in larger amounts, or for longer than prescribed. 


- Do not crush, break, or open an extended-release pill.


- Swallow it whole to avoid exposure to a potentially fatal dose.

- Seizures (convulsions) have occurred in some people taking this medicine.


- Tramadol may be more likely to cause a seizure if you have a history of seizures or head injury, a metabolic disorder, or if you are taking certain medicines such as antidepressants, muscle relaxers, narcotic, or medicine for nausea and vomiting.

- Tramadol may be habit-forming, even at regular doses.


-Take this medicine exactly as prescribed by your doctor. 


-Never share the medicine with another person.


- Tell your doctor if you are pregnant.Tramadol may cause life-threatening addiction and withdrawal symptoms in a newborn.


- Do not crush the tramadol tablet.

* You should not take tramadol if you are allergic to it, or if you have:
- severe asthma or breathing problems .
- a blockage in your stomach or intestines .
- if you have recently used alcohol, sedatives, tranquilizers, or narcotic medications.
- a history of head injury, epilepsy or other seizure disorder;
- a history of drug or alcohol addiction .
- a metabolic disorder .
- if you are also using certain medicines to treat migraine headaches, muscle spasms, depression, mental illness, or nausea and vomiting.

* To make sure tramadol is safe for you, tell your doctor if you have:
- liver or kidney disease. 
- a stomach disorder .
- a history of drug abuse, alcohol addiction, mental illness, or suicide attempt.
- Tramadol is more likely to cause breathing problems in older adults and people who are severely ill, malnourished, or otherwise debilitated.
- FDA pregnancy category C. It is not known whether this medicine will harm an unborn baby.

- Tramadol may cause breathing problems, behavior changes, or life-threatening addiction and withdrawal symptoms in your newborn if you use the medication during pregnancy. 
- Tell your doctor if you are pregnant.
- Tramadol can pass into breast milk and may harm a nursing baby. 

- You should not breast-feed while you are taking this medicine.
- Do not give this medication to anyone younger than 16 years old without the advice of a doctor.

- Ultram ER should not be given to anyone younger than 18 years old.
- Rybix ODT may contain phenylalanine. Talk to your doctor before using this form of tramadol if you have phenylketonuria (PKU).


* How should I take tramadol?
- Take tramadol exactly as prescribed. 

- Follow all directions on your prescription label. 
- Tramadol can slow or stop your breathing, especially when you start using this medicine or whenever your dose is changed.
- Never take in larger amounts, or for longer than prescribed. - Tell your doctor if the medicine seems to stop working as well in relieving your pain.
- Stop taking all other around-the-clock narcotic pain medications when you start taking tramadol.
- Tramadol can be taken with or without food, but take it the same way each time.


 * Tramadol side effects :


- Get emergency medical help if you have any of these signs of an allergic reaction to tramadol: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

- Call your doctor at once if you have:
seizure (convulsions);
weak or shallow breathing;
high levels of serotonin in the body-agitation, hallucinations, fever, fast heart rate, overactive reflexes, nausea, vomiting, diarrhea, loss of coordination, fainting; or
severe skin reaction--fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.


* Common tramadol side effects may include:
headache, dizziness, drowsiness, tired feeling;
constipation, diarrhea, nausea, vomiting, stomach pain; or
feeling nervous or anxious.
itching, sweating, flushing (warmth, redness, or tingly feeling).

- This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.


* Tramadol dosing information :
Usual Adult Dose for Pain:
For mild to moderate severe chronic pain not requiring rapid onset of analgesic effect:
Initial dose: 25 mg every morning
Titration: increase in 25 mg increments as separate doses every 3 days to reach 100 mg per day taken as 25 mg 4 times per day. Then the total daily dose may be increased by 50 mg as tolerated every 3 days to reach 200 mg per day taken as 50 mg 4 times per day.
Maintenance: After titration, tramadol 50 mg to 100 mg can be administered as needed for pain relief every 4 to 6 hours not to exceed 400 mg per day.

For the management of moderate to moderately severe chronic pain in adults who require around-the-clock treatment of their pain for an extended period of time:
Extended-Release Tablets:
Initial Dose: 100 mg once daily and titrated up as necessary by 100 mg increments every five days to relief of pain and depending upon tolerability.
Maximum Dose: Extended-release tablets should not be administered at a dose exceeding 300 mg per day.

For patients in whom rapid onset of analgesic effect is required and for whom the benefits outweigh the risk of discontinuation due to adverse events associated with higher initial dose:
Dose: 50 mg to 100 mg can be administered as needed for pain relief every 4 to 6 hours, not to exceed 400 mg per day.

Tramadol Extended-Release (ER):
Patients not currently treated with tramadol immediate-release (IR):
Initial dose: 100 mg once daily and titrated up as necessary by 100 mg increments every 5 days to relief of pain and individualized according to patient need and tolerability.
Maximum dose: 300 mg per day
Patients currently on tramadol IR (immediare release) :
Calculate the 24-hour tramadol IR dose:
Initial dose: Round down to the next lowest 100 mg increment. The dose may subsequently be individualized according to patient need and tolerability.
Maximum dose: 300 mg per day
Due to limitations in flexibility of dose selection with tramadol ER, some patients maintained
on immediate release products may not be able to convert.

Usual Geriatric Dose for Pain:

For patients over 65 years:
Dose selection should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function and of concomitant disease or other drug therapy.

For patients over 75 years:
Maximum dose of regular oral tablets: 300 mg per day in divided doses

Usual Pediatric Dose for Pain:
4 to 16 years:
Immediate release formulations: 1 to 2 mg/kg/dose every 4 to 6 hours
Maximum single dose: 100 mg
Maximum total daily dose is the lesser of: 8 mg/kg/day or 400 mg/day

16 years and older:
Initial dose: 50 to 100 mg every 4 to 6 hours
Maximum dose: 400 mg/day
Alternatively, for patients not requiring a rapid onset of effect, side effects may be decreased by initiating dosage at 25 mg/day and increasing by 25 mg every 3 days up to 25 mg 4 times a day. Dosage may then be increased by 50 mg every 3 days as tolerated to 50 mg 4 times a day.

16 years and older:Oral disintegrating tablet (ODT):
Initial: 50 to 100 mg every 4 to 6 hours
Maximum: 400 mg/day
Alternatively, for patients not requiring a rapid onset of effect, side effects may be decreased by initiating dosage at 50 mg/day and increasing by 50 mg every 3 days up to 50 mg 4 times a day.
Maximum: 400 mg/day

16 years and older:Extended-release formulations:
Initial: 100 mg once daily
Titrate by 100 mg increments every 2 to 3 days if needed for pain control
Maximum: 300 mg/day


Finally notice that :

- Not all possible interactions are listed here. 
- Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

For more information read all report on 

http://www.drugs.com/

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